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In previous works Wang et al
2020-10-23

In previous works (Wang et al. [4,5]), the PR-CPA EoS has been applied to describe the solubilities of hydrocarbons (including methane, ethane, propane, n-butane, n-pentane, n-hexane, benzene, toluene, and ethyl-benzene) and mercaptans (including methyl mercaptan and ethyl mercaptan) in aqueous MDEA
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A growing number of other
2020-10-23

A growing number of other post-translational modifications are implicated in regulation of the ubiquitin system, including substrate modification by hydroxylation, glycosylation, acetylation, methylation, modification by poly(ADP-ribose) (PAR), and attachment of ubiquitin-like modifiers. The HIF1-α
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br Acknowledgements The study of RING type E s continues
2020-10-23

Acknowledgements The study of RING-type E3s continues to grow extremely rapidly. We regret that it was possible to only cite a fraction of the outstanding primary publications in this field. This work was supported by the National Institute of General Medical Sciences grants R01 GM088055 and R01
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In the phase I AURA
2020-10-22

In the phase I AURA trial, patients with EGFR activating mutations and centrally confirmed tumor and/or plasma genotyping (BEAMing) T790M result were enrolled. Among 216 patients with both plasma and tissue genotyping results, the concordance rate was 82% for ARRY-142886 receptor 19 deletions, 86%
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The effect of NAT deletion on mitochondrial function in
2020-10-22

The effect of NAT1 deletion on mitochondrial function in MDA-MB-231 neurokinin 1 receptor has been reported elsewhere (Carlisle et al., 2018). However, unlike the data presented here, increases in reserve capacity and glycolytic reserve were seen. The reasons for this variance between our study and
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Several single nucleotide polymorphisms SNPs in
2020-10-22

Several single nucleotide polymorphisms (SNPs) in humans affect CYP3A expression and activity (Lamba et al., 2002). The CYP3A4 SNP rs2740574 (also referred to as CYP3A4*1B, by The Human Cytochrome P450 (CYP) Allele Nomenclature Database, http://www.cypalleles.ki.se/) is a change in the promoter regi
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We then analyzed Ki proliferation
2020-10-22

We then analyzed Ki-67 proliferation index as a categorical variable by using 15%, essentially the median Ki-67 value in the entire study group (see above), to delineate low and high proliferation subgroups. By Fisher\'s exact test, both the type 1 versus non-type 1 EWS-FLI1 comparison (P = 0.047; T
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br Experimental Procedures br Author Contributions br Acknow
2020-10-22

Experimental Procedures Author Contributions Acknowledgments Introduction Estrogen-related receptors (ERRα, ERRβ, and ERRγ) are orphan nuclear receptors whose physiological ligands have not yet been identified. Although ERRs are closely related to estrogen receptors (ERs) they do not res
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br Other pathways involved in the preventive and
2020-10-22

Other pathways involved in the preventive and therapeutic potential of flavonoids in neurodegenerative diseases Rather than the induction of MAPK/ERK pathway, flavonoids actively modulate other critical intracellular neuronal survival and death protein kinases pathways, more importantly PI3K/Akt,
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ras inhibitor br Introduction Breast cancer is
2020-10-22

Introduction Breast cancer is the most common malignant tumor in women and the second leading cause of female death [1]. In recent years, with the improvement of early detection and the emergence of new treatment methods, the mortality rate of breast cancer has been greatly reduced. However, the
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iap apoptosis br Material and methods br Results br
2020-10-22

Material and methods Results Discussion Cysticerci located in host tissues are exposed to several effector mechanisms of the immune system (Flisser et al., 1986; Sciutto et al., 2000; Amit et al., 2011; Singh et al., 2013). In addition, the extensive uptake of host proteins by cysticerci ha
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As before all calculations are based on
2020-10-22

As before [3], [4], all calculations are based on thermodynamically first- and second-order hydropathic (amino acid) scales [6], [7], linearly scaled to a common center and a common range for each of the 20 amino acids. These are then converted to a triangular matrix , where is the length of a sli
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One of the most frequent
2020-10-22

One of the most frequent gene alterations in MM is methylation of the p15 and p16 genes in the 5′ upstream region. P15 and p16 proteins are Masitinib australia regulators involved in the inhibition of transition from G1 to S phase. Frequencies of p15 or p16 gene methylation up to 32% and 53%, resp
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Increasing evidence suggests that normal vaginal delivery is
2020-10-21

Increasing evidence suggests that normal vaginal delivery is a natural inflammatory process which results in increased levels of cytokines like Interleukin-6 (IL-6), Interleukin-8 (IL-8) in maternal and cord blood plasma [10]. Increased levels IL-6 and IL-8 have been reported in the amniotic fluid o
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Elevated production of cysLTs in asthma and rhinitis in gene
2020-10-21

Elevated production of cysLTs in WAY-100635 maleate salt australia and rhinitis in general and aspirin-sensitive disease in particular10, 11, 26, 27 has been implicated in causing epithelial cell activation and excessive mucus secretion, which characterize these diseases.2, 28 It is of particular in
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