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br Conflict of interest br Introduction Over
2019-04-17
Conflict of interest Introduction Over the last several decades, substantial research interest has been focused on characterizing the pathophysiological substrate underlying atrial fibrillation (AF) [1]. AF is a complex arrhythmia and has been shown to be temporally variable, so that AF durati
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Qu dicen las fechas en que se ha
2019-04-17
¿Qué dicen las fechas en que se ha flexibilizado la posición de ambas partes? Veamos una cita elocuente sobre la situación internacional en la década de los años setenta del siglo pasado, marco en el que se mejoraron las relaciones entre Washington y La Habana, bajo el gobierno de James Carter. Por
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El poema arranca de una contemplaci
2019-04-16
El poema arranca de una contemplación del paisaje en pleno mes de noviembre. El “verdor” de las siemprevivas contrasta con un panorama vegetal dominado por la “grisura” de la deshojadura otoñal. La mirada del yo poético se fija preferentemente “en las siemprevivas y en las plantas perennes”. Esta pe
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br History of cholesterol and
2019-04-16
History of cholesterol and bile fasudil research Bile is a yellow, brownish, or olive-green liquid that is composed primarily of water, organic solutes (such as lipids), inorganic salts, and some proteins. In bile, cholesterol, phospholipids, and bile acids are three major lipids, and bile pigme
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br Discussion Sato et al first reported TCM
2019-04-16
Discussion Sato et al. [11] first reported TCM in 1990, and thereafter, numerous cases were reported in the late 2000s. In 85% of the cases, TCM onset was preceded by an emotional or physical stress event, however, in 15% of the cases, the presence of a stress trigger could not be detected [2]. M
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br Conclusions br Limitation br Acknowledgments This
2019-04-16
Conclusions Limitation Acknowledgments This research was supported in part by the China Postdoctoral Science Foundation (Nos. 2013M542478 and 2015T81139), a Grant (no. 2014FB059) from the Joint Special Funds for the Department of Science and Technology of Yunnan Province-Kunming Medical Uni
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br Ethics br Funding br Conflicts of interest br
2019-04-16
Ethics Funding Conflicts of interest Acknowledgments Case A 68-year-old man with palpitations was referred to our center for catheter ablation because of drug-refractory atrial fibrillation (AF). The preoperative multidetector computed tomography showed a congenital vascular anomaly:
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Education and lifestyle changes for the
2019-04-16
Education and lifestyle changes for the prevention of arrhythmias are critical in BrS. Patients should be informed of the various modulators and precipitating factors that could cause malignant arrhythmias. A prominent S-wave in Lead I has recently been identified as an ECG marker of BrS [298A]. Fev
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br Results Compared to the respective untreated groups the V
2019-04-16
Results Compared to the respective untreated groups, the VT duration was shorter in clonidine-treated ETB-deficient rats during phase I and in wild-type rats during phase II (Fig. 1A). Heart rate (HR) increased in both untreated groups, but this response was blunted after clonidine, mainly in ETB
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br Consideracj es fin is De acordo
2019-04-16
Consideracjóes fináis De acordo com as evidências coletadas com ask1 inhibitor pesquisa, algumas discussões passam a ser sugeridas. Inicialmente, das parcerias entre Estado e sociedade foram abertas vagas na saúde públicas a serem ocupadas por “pessoas jurídicas de direito privados”, e mesmo sem
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The medical environment in Asian Pacific countries is
2019-04-15
The medical environment in Asian-Pacific countries is widely different from that in Western countries in terms of disease prevalence, CIED implant rates, and other parameters. Moreover, there are remarkable differences in the manner patients are followed-up among the countries in the Asian-Pacific r
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However it should be noted that large proportion
2019-04-15
However, it should be noted that large proportion of patients develop at least one SRE after BTAs purchase Aminoallyl-dUTP (74/155, 48%) appearing to be in keeping with the results of randomised BTA trials [3–6]. Indeed, for those patients who had not had an SRE prior to commencing a BTA, their risk
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Mechanistic target of rapamycin mTOR a highly
2019-04-15
Mechanistic target of rapamycin (mTOR), a highly conserved serine-threonine protein kinase, is a key regulator of cell growth and metabolism. As discussed above, mTORC1 is a negative regulator of the preinitiation complex that modulates the initiation of autophagosome biogenesis. Pharmacological and
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When the analysis was matching with propensity score OS
2019-04-15
When the analysis was matching with propensity score, OS was still significantly longer in JAK2+ patients (median not reached versus 73 months, p=.031) whereas JAK2 status had no significant prognostic value for OS in IPSS intermediate-2 and high patients (p=.18). Discussion In this series, whic
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Chronic immunosuppression has been reported to be linked wit
2019-04-15
Chronic immunosuppression has been reported to be linked with PEL [11]. Several patients with concomitant PEL and HIV infection were reported. Thus, a small portion of the elderly with immunosuppressive conditions may have a tendency to develop MALT lymphoma. Our elderly patient had no HIV infection
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