• br Tuberculosis remains a global emergency and continues to

  2019-05-05

  

  Tuberculosis remains a global emergency and continues to present major public health challenges worldwide. The actual global burden of tuberculosis can only be estimated because no accurate data are available from national country programmes from of high tuberculosis endemic countries. The WHO 201

• br Clinical evidence to support that PES

  2019-05-04

  

  Clinical evidence to support that PES predicts cardiac events in BS Brugada et al. were the first to propose that inducibility of sustained ventricular arrhythmias with PES is useful to identify patients who are at high risk of SCD [3]. During follow-up of patients with spontaneous type 1 Brugada

• Introduction The Space Shuttle has been retired and the Inte

  2019-05-04

  

  Introduction The Space Shuttle has been retired and the International Space Station (ISS) will be in use until 2020 (Fig. 1). Scientists and engineers are thinking about a mission to Mars in the future. Human exploration of space is at a turning point, and a number of questions about the future of

• br Discussion Digoxin has multiple effects on

  2019-05-04

  

  Discussion Digoxin has multiple effects on the myocardium and has multiple cardiac-related uses. In the treatment of atrial fibrillation, digoxin increases vagal tone to prolong the refractory Ki16425 at the AV node, decreasing ventricular response to higher atrial rates [3]. Toxic doses of digox

• Haemorrhagic stroke was once a major cause of death in

  2019-05-04

  

  Haemorrhagic stroke was once a major cause of death in high-income nations, but its importance has receded in those regions over the 20th century. Our results suggest that, in the first decade of the 21st century, haemorrhagic stroke remains an important cause of death and disability worldwide. With

• br El hispanismo criollo de vasconcelos br

  2019-05-04

  

  El hispanismo criollo de vasconcelos Conclusiones: “próspero” vasconcelos Sin la disciplina personal ni el pragmatismo, inculcado por la pequeña escuela texana, Vasconcelos no hubiera logrado todo lo que se propuso desde joven. El peligro de la dispersión y la pereza latinoamericana ya lo habí

• Un segundo aspecto que deber

  2019-05-04

  

  Un segundo aspecto que debería ser considerado para entender cabalmente por qué estas parentelas nobiliarias indígenas de Xolloco Acatla mostrarían una notable reluctancia haspin inhibitor relacionarse con los poderes de San Pablo, y, por el contrario, habrían exhibido una interesada vinculación con

• People in LMICs are disproportionately exposed to severe

  2019-05-04

  

  People in LMICs are disproportionately exposed to severe acute kidney injury and have substantially less access to effective treatment than do people in higher-income countries. Framing acute kidney injury as a driver of substantial inequity in disease risk and mortality in low-resource countries, t

• GPCR Compound Library Introduction Multiple myeloma MM is th

  2019-04-30

  

  Introduction Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with 80–90% of patients developing bone lesions during their disease course [1]. Myeloma bone lesions are purely osteolytic and are associated with severe and debilitating bone pain, pathologic fractures, hyperca

• Both stunting and environmental enteric dysfunction improve

  2019-04-30

  

  Both stunting and environmental enteric dysfunction improve with radical shifts in environment, such as Seliciclib or local economic development. This improvement is reflected to some extent by the smoothing of the seasonality of undernutrition reported by Nabwera and colleagues in these three Gambi

• Most spinal schwannomas derived from Schwann

  2019-04-30

  

  Most spinal schwannomas derived from Schwann stavudine along the dorsal sensory roots involve radicular pain as the most common initial symptom. However, symptoms may be subtle and progress slowly over time, owing to the slow-growing nature of these tumors. In our case, it\'s more difficult to thin

• The authors of the NCCN non small

  2019-04-30

  

  The authors of the NCCN non-small cell lung cancer guidelines provide the most guidance about radiotherapy dosing for painful bone metastases of any of the primary sites evaluated [39]. Bone metastases due to non-small cell lung cancer are separated into those “with soft tissue mass” versus those “w

• In silico prediction software SIFT PolyPhen CADD and other p

  2019-04-30

  

  In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com

• Cholangiopathies are a group of rare

  2019-04-30

  

  Cholangiopathies are a group of rare diseases whose primary or secondary target is the cholangiocyte. The onset and subsequent development processes of cholangiopathies are extremely diverse, with causes that are genetic, neoplastic, immune-mediated, idiopathic, infectious, and toxin- or drug-induce

• Gender transformative policy and cultural reforms

  2019-04-30

  

  Gender transformative policy and cultural reforms are also crucial to change prevailing norms and customs that devalue women and girls. Implementation and enforcement of non-discriminatory policies and practices that require gender equity in inheritance, property rights, education, and civil liberti

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