• br Water the main component of Earth s ecosystems concentrat

  2019-06-01

  

  Water—the main component of Earth\'s ecosystems—concentrates some of the most worrying global concerns that have emerged during the Anthropocene. When it comes to health considered at a planetary level, the challenges related to water can be sorted into five main categories: pollution, access to

• Bile acids are cholesterol derivatives produced only in the

  2019-06-01

  

  Bile acids are cholesterol derivatives produced only in the hepatocytes of the liver. Hepatic bile acid synthesis represents the only quantitatively significant route for cholesterol elimination. Bile acids are amphipathic physiological detergents that facilitate dietary cholesterol, lipid and fat-s

• br The L type calcium channel LTCC in heart

  2019-05-31

  

  The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot

• The electrophysiological mechanisms underlying high frequenc

  2019-05-31

  

  The electrophysiological mechanisms underlying high frequency activity observed in the PLA during SRAF could be reentry (rotor) or focal discharges (triggered activity). To discriminate between these mechanisms, we perfused ryanodine (10–40μM) or caffeine (5mM) to abolish calcium overload-mediated t

• br Associated heart disease in

  2019-05-31

  

  Associated eicosapentaenoic acid disease in children with ICD implantations In a multicenter ICD registry of 443 patients [8], 69% of the patients had CHD and 23% had cardiomyopathy. The most common heart disease was tetralogy of Fallot (19%), followed by hypertrophic cardiomyopathy (14%) (Fig.

• Desde otro contexto Andy Hargreaves planteaba en el a

  2019-05-30

  

  Desde otro contexto, Andy Hargreaves planteaba en el año 2000 que las relaciones de la familia y la escuela también se tensionan en torno membrane transport la estandarización: En el contexto internacional, tal como lo hemos ejemplificado del sistema escolar formal, Mathew Malkan plantea que los pr

• In high income settings the prevalence of tobacco use

  2019-05-30

  

  In high-income settings, the prevalence of tobacco use has been shown to be significantly higher in people living with HIV than among HIV-negative individuals of the same age and sex distribution. This at-risk pattern is one of the biggest threats to the number of years of life saved with antiretrov

• ppar pathway The authors of the NCCN non small cell lung can

  2019-05-30

  

  The authors of the NCCN non-small cell lung cancer guidelines provide the most guidance about radiotherapy dosing for painful bone metastases of any of the primary sites evaluated [39]. Bone metastases due to non-small cell lung cancer are separated into those “with soft tissue mass” versus those “w

• beta lactamase inhibitor br Ya desde el siglo xvi Salinas pa

  2019-05-30

  

  Ya desde el siglo xvi, Salinas parece aceptar las innovaciones de Ramos Pareja que avanzaban en el siglo xv sobre lo que sería el temperamento igual. La obra de Salinas, Siete libros sobre la música, de 1577, entabla una explícita afinidad con las teorías de su contemporáneo Zarlino, como éste bet

• br In Gretchen Stevens and

  2019-05-30

  

  In Gretchen Stevens and colleagues\' update of global, regional, and national trends in haemoglobin concentration and levels of anaemia emphasises both the massive extent of the problem, and its very slow rate of improvement. About 30% or more of women and children younger than 5 years are affect

• br Transici n y representaci n Qu pas con

  2019-05-29

  

  Transición y representación ¿Qué pasó con esa idea del campesino nacional, anacrónico y en conflicto con la modernidad en el momento posrevolucionario? Su reinscripción como una idealización coincide con los pactos de transición de régimen. A la vez, la participación militar de los campesinos com

• Para Rozitchner la di spora proporcionaba la posibilidad de

  2019-05-29

  

  Para Rozitchner, la diáspora proporcionaba la posibilidad de averiguar por qué los sujetos políticos de los años setenta —entre los que se incluía— produjeron una fantasía y una idealidad sobre la materialidad de las fuerzas históricas. Y también, de advertir por qué el terror fue negado y excluido

• br Contribution br Acknowledgments and

  2019-05-29

  

  Contribution Acknowledgments and disclosures Introduction Following HSCT a complex immune reconstitution (IR) is observed. When the infused CD34+cells (CD34+i) begin to proliferate, an increase in peripheral blood rora is detected. Lymphocytes require more time than granulocytes in order t

• We also looked at antithrombotic

  2019-05-29

  

  We also looked at antithrombotic therapy for each CHADS2 score in each country. For patients with CHADS2 score of 0 (Fig. 3), approximately 80% of the physicians used antiplatelet agents in 6 of the countries—Australia, China, Korea, Taiwan, Hong Kong, and Singapore. A total of 59% of the physicians

• URMC-099 br Introduction Patients with advanced breast prost

  2019-05-29

  

  Introduction Patients with advanced breast, prostate, lung and colo-rectal cancer frequently develop bone metastases (BMs). These lesions may be asymptomatic or may cause pain, pathologic fractures, malignant hypercalcemia, epidural spinal cord compression and/or shorten survival [1]. The underly

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